If we are doing Canton and want to avoid the typical places on the Square as Chris alludes to, which I think is a good idea, I would suggest Cardinal Tavern, Hudson Street Stackhouse, Smaltimore, or Pig & Rooster (haven't actually been to this place since it switched to new ownership by the folks that run Chasseur, but I've heard good things).
Some of those places aren't huge, so if we have more than 8 or so, maybe one of the larger places would be better. Hudson St and Smaltimore do have plenty of space.