Lots of sound advice already offered...
Things I would emphasize that have already been said...
1. She should see the guidance counselor every day... the point being to (a) show how serious she is, and (b ) make the counselor think of her first without the counselor even realizing he/she is doing it.
2. A degree from Yale or Harvard carries a lot more weight than it should. 25 years from now, it could make the diff between her getting the job she wants vs. somebody else. It might not, but also it well might. This is completely crazy and unfair, but it's still true anyway. It also can provide a people-you-know network, plus a people-you-don't-know-that-can-help-you-anyway-just-based-on-the-school network, that can connect her with opportunities in the future. It's the equivalent of semper-fi for people from the same brand-name school...
3. You should complete ignore how much money any school is giving her, and focus *only* on how much it actually costs in the end. In general, the way financial aid works (unless they've changed something) is that the net out-of-pocket cost to the family will be the same, regardless if it's a megabucks private school vs. Anytown State College. Which leaves the diff in student loans. Sometimes, the cost to the family will be the same but the student is loaded down with crazy loans that make graduating like having a mortgage without the house. But sometimes it's not all shifted to loans, sometimes they lower the cost a ton, based on the family's income. I know Stanford does this routinely, the only kids they hose are from families who can afford it. But I don't know beans about what Yale does.
4. Most kids wind up doing stuff different than they think when they first enter college. Lots of kids don't change their minds, but most do. If she wants to go to the biology place, well, there's nothing wrong with having a biology degree, it can be a door opener to lots of different things. Any real science can be. And by "real science", I mean a science that doesn't have the word "science" in it's name.